C&O Canal 100

Knoxville, United States • 24 Apr 2027

C&O Canal 100 : event description

The C&O Canal 100 is a 100 mile ultramarathon held near Knoxville, Maryland along the C&O Canal towpath. The course consists of one approximately 40 mile loop followed by two approximately 30 mile loops, with most miles close to the Potomac River and the Appalachian mountains. The race starts, has its halfway point, and finishes at Camp Manidokan and runs between Antietam and Brunswick, MD.

Organizers place about seven aid stations on each loop; some stations are encountered multiple times. Distances between aid stations range from 3 to 6.9 miles. The event takes place in spring conditions that organizers describe as temperate, on a course with low elevation and smooth terrain.

Participant comments included praise for volunteer support and well stocked aid stations. The event is listed as a WSER 2027 qualifier. Registration opens on January 1, 2027 at 12:00 AM ET. Visit the organization's website for the most recent information.

Race information

100 mi
100 Miler
Visit the organization's website for the most recent information.
Trail runs nearby

Two days of fundraising hikes in May 2026 offer 5K and 10K canal routes plus 10 and 20 mile Appalachian Trail challenges, with trail support, fundraising matches, and proceeds benefiting Micah’s Backpack and the Refugee Welcome Network.

A two-part fundraising hike in May with Challenge options on the Appalachian Trail and 5K/10K hikes on the C&O Canal, supporting Micah’s Backpack and the Refugee Welcome Network; individual fundraising is matched 2-to-1.

A backyard ultra in Knoxville, Maryland where runners complete a 4.167 mile yard each hour until only one finishes. The event includes a 1-mile option, offers prize money for top finishers, and serves as a Backyard Ultra qualifier.

Trail run and walk on May 30, 2026 at Gentle Giants Draft Horse Rescue in Mt. Airy, MD featuring 1 mile and 5K courses across forest trails and open pasture with draft horses on the farm.

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