C&O Canal 100

Knoxville, United States • 25 Apr 2026

The C&O Canal 100 is a 100-mile ultramarathon held in Knoxville, Maryland, along the scenic C&O Canal towpath near the Potomac River and Appalachian Mountains. The course features one approximately 40-mile loop followed by two 30-mile loops, starting and finishing at Camp Manidokan. Runners enjoy a fast, friendly route with low elevation and smooth terrain, ideal for first-time 100-milers and veterans seeking personal bests. The race offers about seven aid stations per loop, spaced 3 to nearly 7 miles apart, providing excellent support with well-stocked supplies and enthusiastic volunteers. The event is known for its beautiful riverside scenery and temperate spring weather. Visit the organization's website for the most recent information.

Race information

100 mi
100 Miler
Visit the organization's website for the most recent information.
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