C&O Canal 100

Knoxville, United States • 25 Apr 2026

Event overview

The C&O Canal 100 is a 100-mile ultramarathon in Knoxville, Maryland held on April 25, 2026. The race starts, reaches halfway, and finishes at Camp Manidokan. The course runs along the C&O Canal towpath between Antietam and Brunswick, following the Potomac River and running near the Appalachian mountains. Registration opens January 1, 2026. The event is a WSER 2026 qualifier.

Course and support

The route is composed of one approximately 40-mile loop plus two approximately 30-mile loops.

  • ~40-mile loop
  • ~30-mile loops (two repeats)

There are about seven aid stations placed around each loop, with some stations visited multiple times. Distances between aid stations range from 3 to 6.9 miles. The course is described as low elevation with smooth terrain and takes place in temperate spring weather. Volunteers staff the aid stations, which are described as well stocked. Visit the organization's website for the most recent information.

Race information

100 mi
100 Miler
Visit the organization's website for the most recent information.
Trail runs nearby

Run the Patriotic Pursuit in Williamsport Park with 5k, 10k and half marathon options along the scenic flat C&O Canal Trail by the river. Chip timing, tech shirts, finisher medals and a virtual option support Semper Fi & America's Fund.

Test your limits on this timed trail ultra at Little Bennett Campground with 5 and 9 hour solo and relay options on a scenic 4.4 mile loop. Enjoy aid stations, Altra demos and a post race chili while supporting Montgomery Parks Foundation.

Join the scenic Seneca Creek Greenway Trail in Gaithersburg MD on March 7, 2026 for a marathon or an extended 50K. Run single track parkland trails and choose to finish at the marathon or keep going to complete the 50K.

Run a flat, out and back 5k or 10k along Brunswick's scenic gravel path and support Wear Blue: Run to Remember. Finishers get a medal, technical shirt and a beer, with virtual options available for out of town runners.