C&O Canal 100
Knoxville, United States • 25 Apr 2026
Event overview
The C&O Canal 100 is a 100-mile ultramarathon in Knoxville, Maryland held on April 25, 2026. The race starts, reaches halfway, and finishes at Camp Manidokan. The course runs along the C&O Canal towpath between Antietam and Brunswick, following the Potomac River and running near the Appalachian mountains. Registration opens January 1, 2026. The event is a WSER 2026 qualifier.
Course and support
The route is composed of one approximately 40-mile loop plus two approximately 30-mile loops.
- ~40-mile loop
- ~30-mile loops (two repeats)
There are about seven aid stations placed around each loop, with some stations visited multiple times. Distances between aid stations range from 3 to 6.9 miles. The course is described as low elevation with smooth terrain and takes place in temperate spring weather. Volunteers staff the aid stations, which are described as well stocked. Visit the organization's website for the most recent information.