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C&O Canal 100

Knoxville, United States • 25 Apr 2026

The C&O Canal 100 is a 100-mile ultramarathon held in Knoxville, Maryland, along the scenic C&O Canal towpath near the Potomac River and Appalachian Mountains. The course features one approximately 40-mile loop followed by two 30-mile loops, starting and finishing at Camp Manidokan. Runners enjoy temperate spring weather, low elevation, and smooth terrain, making it suitable for both first-time 100-milers and experienced ultrarunners. The race includes about seven aid stations per loop, spaced 3 to nearly 7 miles apart, offering excellent volunteer support and well-stocked supplies. This fast, friendly event is also a qualifier for the Western States Endurance Run. Visit the organization's website for the most recent information.

United States Maryland Knoxville

Race information

Website Registration
100 mi
100 Miler
Visit the organization's website for the most recent information.
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